Physiology of Domestic Animals is divided into 21 chapters.

In each chapter, an introductory ingress is followed by a short description of major aspects in the chapter. The body of the chapter provides a more detailed understanding of the physiological processes. The clinical examples included in the chapters are selected to illustrate the delicate balance between the normal processes of the body. Short statements summarizing central points in the main text are inserted in the margins. These statements are particularly useful when reviewing the chapters. Inserted questions reveal whether adequate understanding of important issues has been achieved. Answers to the questions can be found in the associated main text.

Basic knowledge of physics, chemistry, and biochemistry is required to comprehend physiology. The book contains an introductory chapter presenting an overview of some of the most relevant topics of these fields.

There are no logical boundaries between cell biology and physiology. Knowledge of cell biology is therefore a necessary platform for the understanding of animal physiology. Consequently, the book offers an introduction to cell biology, and describes how cells interact and contribute to the various functions of tissues and organs (chapters two and three).

Frequent cross-referencing emphasizes how individual cells and organs of the body collaborate to create a functional unit.
In the comprehensive and user-friendly index, bold page numbers direct the reader to main descriptions or definitions, whereas numbers in italics refer to figures.